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KMID : 0387720170280020177
Korean Journal of Blood Transfusion
2017 Volume.28 No. 2 p.177 ~ p.182
A Case with Changes in Autoantibodies with Mimicking Specificity in a Patient with Hepatocellular Carcinoma
Lim Hyeon-Ho

Kim Kyeong-Hee
Jeong Gi-Cheol
An Gyu-Dae
Woo Kwang-Sook
Han Jin-Yeong
Kim Jung-Man
Abstract
Changes in autoantibodies with mimicking specificity for Rh antigens are quite rare. Here, we report a 73-year-old male patient with hepatocellular carcinoma that showed changes in the autoantibodies with mimicking specificity. He was admitted to our hospital with mental alterations and hypoglycemia. The antibody identification test for RBC transfusion showed a pattern of agglutination, suggesting anti-E alloantibody and anti-c autoantibody. The patient was then diagnosed with hepatocellular carcinoma, and after 18 months, the antibody identification test showed a different pattern of agglutination, suggesting anti-E alloantibody and anti-C autoantibody. We recommend a careful evaluation to make sure an appropriate transfusion is performed when encountering fluctuating autoantibodies with mimicking specificity.
KEYWORD
Autoantibody, Mimicking specificity, Autoimmunization, Transfusion
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